abstract：BACKGROUND:The differential diagnosis of pancreatic cancer and focal forms of autoimmune pancreatitis is complicated since serological tests, IgG4 and CA 19-9 have a low sensibility and specificity. CT scan and magnetic resonance imaging provide clear differentiation in the majority, but not in all cases. Endosonograph...

journal_title：Revista medica de Chile

authors： Berger Z

更新日期：2014-04-01 00:00:00

abstract：:Professor Raúl B. Etcheverry, M.D., was a founder of Chilean Hematology back in the 1940's and a practicing physician and teacher until an advanced age. Being a superb clinician, he was admired by his ability to unveil from the most common to the most difficult diagnosis of blood disorders and neoplasms by examining b...

journal_title：Revista medica de Chile

authors： Reyes B H

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Despite the low frequency of thyroid nodules (TN) in children, one of every four is malignant. Fine-needle aspiration cytology (FNAC) has a high accuracy detecting thyroid cancer. AIM:To evaluate the performance of FNAC in TN in Chilean children to detect thyroid cancer. PATIENTS AND METHODS:The pathologic...

journal_title：Revista medica de Chile

authors： Grob F,Carrillo D,Martínez-Aguayo A,Zoroquain P,Solar A,Nicolaides I,González H

更新日期：2014-03-01 00:00:00

abstract：:While some genetic factors may explain the development of cancer, its main causes are related to environmental exposure to carcinogenic agents as well as to the effect of determined lifestyles and habits. Several epidemiological studies have shown a consistent relation between obesity and cancer. In non smokers, obesi...

journal_title：Revista medica de Chile

authors： Sánchez R C,Ibáñez C,Klaassen J

更新日期：2014-02-01 00:00:00

abstract：:Equity has been recognized as one of the driving principles of many health systems in the world. In Latin America, Chile has led the explicit inclusion of equity in their health policies, which is reflected in its recent health reform. On the other hand, Chile faces the challenge of defining and implementing a policy ...

journal_title：Revista medica de Chile

authors： Espinoza MA,Cabieses B

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Professional Social Responsibility is now imperative for the practice of medicine. However, there are no instruments to assess it among physicians. AIM:To construct and evaluate the factorial structure and reliability of a questionnaire designed to measure socially responsible behavior in physicians. MATER...

journal_title：Revista medica de Chile

authors： Alvarado DF,Pérez CV,Navarro GS

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Biliary cholesterol is transported by vesicles and micelles. Cholesterol microcrystals are derived from thermodynamically unstable vesicles. In experimental animals vitamin C deficiency leads to a super-saturation of biliary cholesterol and to the formation of gallstones. AIM:To search for a possible relati...

journal_title：Revista medica de Chile

authors： del Pozo R,Muñoz M,Dumas A,Tapia C,Muñoz K,Fuentes F,Maldonado M,Jüngst D

更新日期：2014-01-01 00:00:00

abstract：:Intracranial sinus thrombosis (1ST) after closed head injury is an uncommon but potentially serious complication. It has no correlation with the severity of the injury. The symptoms and clinical course are highly variable. The most frequent but least specific symptom is severe headache. Cerebral lesions and neurologic...

journal_title：Revista medica de Chile

authors： Suárez H F,Mellado T P,Godoy F J

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Aging is the main risk factor to acquire breast cancer (BC). Nevertheless BC in elderly patients is sub-represented in clinical trials. AIM:To describe the clinical characteristics and long term treatment results of localized BC in older women. MATERIAL AND METHODS:Review of medical records of 65 women age...

journal_title：Revista medica de Chile

authors： Sánchez R C,Bakal I F,Camus A M,Besa de C P

更新日期：2013-12-01 00:00:00

abstract：:Due to demographic changes, rising health expenditures, and the reimbursement mechanisms of insurers in the past 30 years, physicians and nurses have had to change the way services are delivered. Concepts such as cost effectiveness and patient safety have also led to the emergence of case management. Case management, ...

journal_title：Revista medica de Chile

authors： Eymin G,Zuleta J

更新日期：2013-11-01 00:00:00

abstract：:Platelet Rich Plasma (PRP) is used in musculoskeletal lesion surgery, including muscle, bone, tendons and ligaments. PRP might accelerate the healing process and the integration of the graft, allowing an earlier return to sports activities of patients. PRP is obtained from autologous blood, which is centrifuged, obtai...

journal_title：Revista medica de Chile

authors： Figueroa P D,Figueroa B F,Ahumada P X,Calvo R R,Vaisman B A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The current recommendations for treatment of patients with newly diagnosed acute promyelocytic leukemia (APL) include all-trans-retinoic acid (ATRA) and anthracycline based chemotherapy. AIM:To evaluate the results of the Chilean protocol following the LPA99 regimen of the Spanish PETHEMA group, except for ...

journal_title：Revista medica de Chile

authors： Undurraga MS,Puga B,Cabrera ME,Palma T,Rossle A,Vergara CG,Rojas B,Aspillaga A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:KRAS oncogene is involved in colorectal carcinogenesis in 22 to 45% of cases. AIM:To determine the frequency, types and distribution of KRAS mutations in colorectal cancer. MATERIAL AND METHODS:KRAS mutations studies were carried out in primary tumors and metastases of colo-rectal cancer from 56 women aged...

journal_title：Revista medica de Chile

authors： Roa I,Sánchez T,Majlis A,Schalper K

更新日期：2013-09-01 00:00:00

abstract：:Stem cells have drawn extraordinary attention from scientists and the general public due to their potential to generate effective therapies for incurable diseases. At the same time, the production of embryonic stem cells involves a serious ethical issue concerning the destruction of human embryos. Although adult stem ...

journal_title：Revista medica de Chile

authors： Ventura-Juncá P,Erices A,Santos MJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Determination of Alanine aminotransferase serum levels ([ALT]s) is a sensitive ana reliable test for liver diseases. AIM:To report the prevalence of abnormal [ALT]s in Chilean population and to identify associated variables. METHODS:We analyzed data from a random sub-sample of 2,794 adults surveyed during ...

journal_title：Revista medica de Chile

authors： Tejos R,Padilla O,Pizarro M,Solís N,Arab JP,Margozzini P,Miquel JF,Riquelme A,Arrese M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Clinical reasoning is the most important competente in the training process of a physician. AIM:To develop a method for teaching clinical reasoning based on prototypes of clinical cases. MATERIAL AND METHODS:The study was conducted on sixty-four third year medical students. The study and control groups att...

journal_title：Revista medica de Chile

authors： Montaldo L G,Herskovic L P

更新日期：2013-07-01 00:00:00

abstract：:ANCA (anti-neutrophil cytoplasmic antibodies) associated vasculitis or AAV are a group of diseases with predominant inflammation of small vessels and the presence of detectable ANCA in serum. Due to these common features, it is considered that AAV share pathogenic mechanisms. Consequently, a similar therapeutic approa...

journal_title：Revista medica de Chile

authors： Silva F,Cisternas M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Dopamine agonists (DA) effectively reduce tumor size of macroprolactinomas, with the consequent improvement of eventual visual impairment. AIM:To study the visual outcomes in patients with macroprolactinoma treated with DA. MATERIAL AND METHODS:Retrospective cohort study which included patients with macrop...

journal_title：Revista medica de Chile

authors： Cuevas JL,Fernández V,Rojas D,Wohllk N,González O,Torche E

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Adolescent alcohol and drug consumption are important public health problems in the Chilean young population. AIM:The purpose of this study was to examine the potential ofa data mining approach in scaffolding policy making, using the particular case of differential risks of harmful alcohol consumption in ad...

journal_title：Revista medica de Chile

authors： Marcelo Villalón C,Cuellar C

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:In July 2010 end stage renal disease anemia correction was incorporated to the program of explicit health guaranties of the Ministry of Health. The treatment plan included intravenous iron and erythropoietin. The prescription of these medications carne from the deriving health organizations. AIM:To describe...

journal_title：Revista medica de Chile

authors： González F F

更新日期：2013-05-01 00:00:00

abstract：:Massive pulmonary embolism (PE) is associated with high mortality. There is still a broad assortment of severity classifications for patients with PE, which affects the choice of therapies to use. The main clinical criteria for defining a PE as massive is systemic arterial hypotension, which depends on the extent of v...

journal_title：Revista medica de Chile

authors： Mercado M,Aizman A,Andresen M

更新日期：2013-04-01 00:00:00

abstract：:Brain functioning is mainly intrinsic, not primarily reflexive. This is supported by the high energy requirements of the resting brain (20% of all the energy consumed) which only marginally increases with changes in brain activity. Modern neuroimaging and neurophysiological techniques have led to the discovery of the ...

journal_title：Revista medica de Chile

authors： Vergara E F,Behrens MI

更新日期：2013-03-01 00:00:00

abstract：:Maternally Inherited Diabetes and Deafness (MIDD) is caused by mutations in mitochondrial DNA (mtDNA), mainly m.3243A>G. Severity, onset and clinical phenotype of MIDD patients are partially determined by the proportion of mutant mitochondrial DNA copies in each cell and tissue (heteroplasmy). The identification of MI...

journal_title：Revista medica de Chile

authors： Cataldo LR,Olmos P,Valerie Smalley S,Díez A,Parada A,Gejman R,Fadic R,Santos JL

更新日期：2013-03-01 00:00:00

abstract：:Aspirin use is necessary after a coronary angioplasty. It should not be used in patients with a history of hypersensitivity. However, rapid desensitization protocols have been reported to allow its use in such patients. One of these protocols consists in the administration of progressive doses of aspirin, from 1 to 10...

journal_title：Revista medica de Chile

authors： Veas P N,Martínez G,Jalil M J,Martínez S A,Castro G P

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Approximately 150 subjects per year suffer severe burns in Chile. AIM:To analyze sociodemographic/clinical features and outcomes of severely burned patients. MATERIAL AND METHODS:Retrospective cohort study of 936 patients aged 47 ± 20 years (66% males), admitted to the National Burn Center of Chile between...

journal_title：Revista medica de Chile

authors： Albornoz CR,Villegas J,Peña V,Whittle S

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:The determination of thyroid stimulating hormone (TSH) reference values is critical for the diagnosis of thyroid diseases. AIM:To explore and discuss different definitions to establish TSH reference values using a Chilean national survey sample. MATERIAL AND METHODS:The 2009-2010 Chilean National Health Su...

journal_title：Revista medica de Chile

authors： Mosso L,Margozzini P,Trejo P,Domínguez A,Solari S,Valdivia G,Arteaga E

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Smoking may hamper female fertility, probably modifying ovarian reserve. Antimüllerian hormone (AMH) is an accurate marker for ovarian reserve. AIM:To look for an association between smoking status and plasma AMH concentration. PATIENTS AND METHODS:A cohort of 141 infertile women in a university setting in...

journal_title：Revista medica de Chile

authors： Fuentes A,Escalona J,Céspedes P,Repetto V,Iñiguez G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The Chilean population has inadequate lifestyles and high prevalence of chronic diseases. AIM:To analyze eating behaviors, nutritional status and history of previous diseases, in students of higher education. MATERIAL AND METHODS:Cross-sectional study in students of 54 higher education centers across the c...

journal_title：Revista medica de Chile

authors： Ratner RG,Hernández PJ,Martel JA,Atalah ES

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The detection of cognitive changes (CC) and psychiatric disorders in relapsing remitting multiple sclerosis (MS-RR) contributes to patient clinical monitoring. AIM:To assess the frequency and characteristics of CC and psychiatric disorders in Chilean patients with MS-RR, before starting immunomodulatory tre...

journal_title：Revista medica de Chile

authors： Nogales-Gaete J,Aracena R,Díaz V,Zitko P,Eloiza C,Cepeda-Zumaeta S,Agurto P,González C

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:We report a 56 year old male hypertensive, who presented with a posterior reversible encephalopathy syndrome (PRES) as an initial manifestation of Guillain-Barré syndrome (GBS). His first symptoms were right hemiparesis and hemihypoesthesia, followed by headache, dizziness, dysarthria and a general feeling o...

journal_title：Revista medica de Chile

authors： Urrutia L S,Venegas R E,Figueroa V C,Carrizo C C

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Several genetic polymorphisms of adiponectin have been associated to metabolic diseases as obesity and co-morbidities. AIM:To investigate if there are associations between +45TG, +276GT, -11,377CG y -11,391GA adiponectin SNPs (single nucleotide polymorphism) with obesity in a Chilean children population. M...

journal_title：Revista medica de Chile

authors： Orellana G,Sapunar J,Sáez K,Aguayo C,Calvo C,Radojkovic C,Riffo B,Gleisner A,Asenjo S,Ulloa N

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight lo...

journal_title：Revista medica de Chile

authors： Gompertz M,Montenegro C,Bufadel ME,Defilippi C,Castillo J,Morales C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Genetically programmed adult-type hypolactasia affects 56% of Chilean population. Ideally, diagnosis should be confirmed. AIM:To compare diagnostic yield of genetic test, hydrogen (H2) expiratory test and a validated symptomatic structured survey (SS). MATERIAL AND METHODS:Patients submitted to H2 test ans...

journal_title：Revista medica de Chile

authors： Rollán A,Vial C,Quesada S,Espinoza K,Hatton M,Puga A,Repetto G

更新日期：2012-09-01 00:00:00

abstract：:The association between Good's syndrome (hypogammaglobulinemia and thymoma) with pure red aplasia is very uncommon. We report a 70-year-old male, who had a thymoma excised nine years before. Afterwards, he suffered frequent respiratory infections, which were attributed to a humoral immunodeficiency. Nine years later, ...

journal_title：Revista medica de Chile

authors： Peña C,Intriago M,Muñoz P,Gray AM,Cabrera ME

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:There is paucity of information about viral etiology of community acquired pneumonia in adults. AIM:To investigate the viral etiology of pneumonia among hospitalized patients. MATERIAL AND METHODS:All adults with pneumonia that were hospitalized were prospectively enrolled at Puerto Montt hospital. A micro...

journal_title：Revista medica de Chile

authors： Rioseco Z ML,Riquelme O R,Riquelme O M,Inzunza P C,Oyarzún G P,Agüero O Y,Ferrés G M,Vial C P,Fasce P R,Torres M A

更新日期：2012-08-01 00:00:00

abstract：:Chile has recently entered into force Act No. 20.580, which modifies the legal limits of blood alcohol concentration in drivers and increases the penalties for driving under the influence of alcohol, narcotics or psychotropic substances. The aim of this review was to give an account of the strengths of this new law bu...

journal_title：Revista medica de Chile

authors： González-Wilhelm L,Johnson J,Carnevali R,Ruiz G

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Patients on chronic hemodialysis have a lower immune response to vaccination against hepatitis B virus (HBV) than the general population. AIM:To identify factors that may interfere with immunization against hepatitis B virus (HBV) in Brazilian hemodialysis patients and analyze the evolution of the level of ...

journal_title：Revista medica de Chile

authors： Pereira ZT,Mendoza-Sassi RA

更新日期：2012-07-01 00:00:00

abstract：:Microalbuminuria is a new tool in the management of patients with diabetes mellitus or hypertension. Microalbuminuria is an easily measured biomarker in a urine sample. Urinary albumin to creatinine ratio in first morning urine sample correlates with 24 hours urinary albumin excretion, but it is easier to obtain, and ...

journal_title：Revista medica de Chile

authors： Tagle R,González F,Acevedo M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:On February 27, 2010 a powerful earthquake followed by a tsunami stroke Chile. The study of mortality during this emergency can provide important public health information. AIM:To describe the main characteristics of people who died during the earthquake and the following three months. MATERIAL AND METHODS...

journal_title：Revista medica de Chile

authors： Lastra T J,Guzmán C G,Conejeros R C,Suárez V G,Chávez F O

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:We report a 35-year-old female patient with a one year history of a pustular and painful erythematous dermatitis, located in great folds, pubis and abdomen. She was evaluated in primary health care, receiving antifungal treatment, antimicrobials, topical and systemic non-steroidal anti-inflammatory drugs, wi...

journal_title：Revista medica de Chile

authors： Valenzuela Y,Ramírez C,Bellolio E

更新日期：2012-05-01 00:00:00